re: Just diagnosed with Type 2 Diabetes

Ditto!

My mind is still blown by how fast the change happened. I was pretty fit until I hit about 38, then I let things go to shite. The straw that broke the camel's back was a horrendous gout attack I had in Dec '22. I had read and watched a lot of different things about carnivore prior to that, especially about its effects on gout (had it for years and years prior), and said frick it, I'm all in.

Gout attacks were completely eliminated w/in 5 months. I just was not expecting as much weight loss. Initially I dropped 30lbs in the first 4 months or so, but I've put on 10lbs since then, because I was finally able to workout again.

I know there are different ways to skin a cat, but man, you saying it's a cheat code is perfectly put.

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Not randomized which introduces huge bias.

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What do you get after the randomization protocol is completed?

An observational study.

What do you get after randomization and people decide they don't like the group they were assigned to?

A lot of bias via non-compliance, drop out, or other issues.

Achieving valid randomization in human studies, outside of the lab, is very difficult, if not impossible.

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But you’re right, you can’t guarantee equal weight loss in a study. But you can design it with that goal in mind.

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You don't want to try and control the outcome values, you want to introduce an intervention and then see where the DV lands. If you try to control the DV in some way, that would introduce bias.

If you're talking about trying to make two diets iso-caloric, then see if there are differences, I understand what you mean.

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To be clear, I am not saying that a low carb diet is not a good strategy to treat diabetes. What I’m saying that it’s not the ONLY good strategy

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I agree.

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My mind is still blown by how fast the change happened. I was pretty fit until I hit about 38, then I let things go to shite. The straw that broke the camel's back was a horrendous gout attack I had in Dec '22. I had read and watched a lot of different things about carnivore prior to that, especially about its effects on gout (had it for years and years prior), and said frick it, I'm all in.

Gout attacks were completely eliminated w/in 5 months.

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They try to blame EVERYTHING on meat.

Gurt?
We can say that here.

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You get a randomized study. It is not observational because you have some control of the independent variable.

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You do not get a randomized study (as people think randomized connotes control and rigor), you get randomized group assignment. You only have control of assignment, and assignment is not the independent variable. The relationship between treatment (the IV) and outcome is not controlled. Modern observational studies often use propensity scores to achieve balance in the groups that serves as proxy for randomization, yet the study is still observational. Whether you randomize assignment or use propensity scores, you still end up with an observational study with regard to the relationship between IV and DV.

When you randomize groups to A and B and set them loose, then later look at an outcome, you are now in an observational study. You have no control of the groups, they will do what they want. You have no guarantees that group A follows the A protocol, etc. You can analyze it as an intention to treat model but that provides limited value.

This is not a knock on observational studies. My main point here is that when you think you have a randomized study, with randomization producing a degree of rigor and control, you're most likely not achieving that. People constantly say "randomized" and think it carries some magical wand of rigor and it doesn't.

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Compliance rate is a hugely important factor in the success of any diet, probably the most important. You shouldn’t ignore that data. A study of just the compliant patients would also provide interesting data but introduces major bias.

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Yes, compliance is important. I'm not suggesting you only study the compliant subjects. I'm saying that assuming you have rigor just because you randomize group assignment is going to lead to bias, which is going to be dangerous to the validity of your conclusions because you're not paying attention to it, because you've assumed that randomized group assignment took care of everything and it certainly does not.

You have to look at the data generating mechanism. If you don't, you are playing a dangerous game and won't even know it.

Tukey and others warned us about these things back in the 60s as computing power started to ramp up and people could ask a computer to crunch numbers. They knew that people would start slapping analysis schemes onto research problems without properly understanding the methods, how the data got to be what it is, and so forth. And that's exactly what has happened.

Type 1 diabetic for the last 40 years. A1Cs run in the 4.5 - 4.7 range. I lift five days a week and eat high fat/protein and low carb. I weigh 184 and am 6’1.

Read the book “Diabetes Solution” by Dr. Richard Bernstein. Read it and follow it and lead a long and healthy life.

Hell yes!

Is your sleep improving?

And yes, it's frigging wild how fast you lose weight in the first two weeks. It's mostly water weight, but in no time flat you're going to see more definition all over your body.

Definitely bump this thread when you get your next blood test.

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Is your sleep improving?

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I have OSA so I use my machine every night. I sleep like a baby. I’d love to be able to lose the machine but I was 185 pounds when I was diagnosed so I don’t think that’s in the cards for me.

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eating only lean meat, vegetables, and limited fruit.

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That’s not much different from what we’re doing. I’m not too concerned about the fat though, but I have limited starches/carbs big time. I’m drinking a lot of water also. I know some of it is water weight, but I lost another pound yesterday so I’m down 6 pounds in the 5 days.

Yeah, my SO eats meat or eggs and vegetables for meals, and for snacks, trail mix of nuts and dried fruit. The meat isn’t even totally lean (not just chicken breast.) There are recipes online for the Whole 30 program that i’ve used. That diet also helped my son mostly clear his eczema and 2 other skin conditions (hidradenitis and acne conglobata.) If you follow it, it works. My son fell off the wagon in college, but can go back to it when he gets tired of suffering. ETa the weight difference for my SO between A1C of 8 vs 4.5 was a loss of 7 lbs.