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Estrogen blocker with TRT?
Posted on 2/28/20 at 12:12 pm
Posted on 2/28/20 at 12:12 pm
Pros? Cons? Brand? Dosage? TIA 

Posted on 2/28/20 at 12:26 pm to Hot Carl
Shouldn't need one for true TRT. Estrogen has health benefits, including neuroprotection.
True TRT won't elevate you above natural levels to a place you need estrogen blockers.
True TRT won't elevate you above natural levels to a place you need estrogen blockers.
Posted on 2/28/20 at 12:52 pm to Rep520
quote:
True TRT won't elevate you above natural levels to a place you need estrogen blockers.
Huh? No. Some people's estrogen levels might be fine on a TRT dose but other's will have elevated E2 levels that are above what's considered ideal.
Posted on 2/28/20 at 1:27 pm to lattin1
quote:
Some people's estrogen levels might be fine on a TRT dose but other's will have elevated E2 levels that are above what's considered ideal.
I'm not personally on TRT, but have looked into it a bit. The intent behind TRT shouldn't be to raise test levels above normal to above average.
That alone shouldn't necessitate an estrogen blocker in healthy men. High estrogen correlates heavily to obesity, but that isn't a reason to use a blocker.
There will always be outliers and people who react differently, but from what I've read, starting without estrogen blockers and measuring would be my preference if I went that route. Estrogen blockers can lead to artificially low levels of estrogen, which cone with side effects.
This may be me, but I'd rather control environmental factors and see if you can get to a normal T/E ratio with TRT before you start with estrogen blockers. If estrogen gets too high, you can always add them in, but they come with their own sides.
Posted on 2/28/20 at 1:53 pm to The Dudes Rug
To expand my point, here's a large analysis. Only about 20% of TRT patients had high estradiol and high estradiol generally correlated to higher libido than low estradiol.
PubMed Study
I just think too many people jump to lower being better with estrogen. TRT will generally increase estrogen, but I am heavily of the belief that the minimal effective dose is better, and if you can get a decent ratio and quality of life without an estrogen blocker, it's better.
The same study heavily hints at E blockers being overprescribed.
PubMed Study
I just think too many people jump to lower being better with estrogen. TRT will generally increase estrogen, but I am heavily of the belief that the minimal effective dose is better, and if you can get a decent ratio and quality of life without an estrogen blocker, it's better.
The same study heavily hints at E blockers being overprescribed.
Posted on 2/28/20 at 2:03 pm to Hot Carl
Also, look into Proviron (Mesterolone). On top of your TRT, it will boost your free T levels and even help mildly with estrogen without being a full blown aromatase inhibitor.
Posted on 2/28/20 at 3:25 pm to Rep520
Fair enough. And I haven’t started TRT, just researching. If an estrogen blocker were to be necessary, would a prescription be preferred or the NIM + BioPerine OTC supplement needs preferred?
Posted on 2/28/20 at 4:40 pm to Hot Carl
Prescription. You want something your doctor is monitoring.
There are different types. Some can just crush estrogen, which more research is suggesting has a lot of sides. Some are less drastic and will just reduce the level, not eliminate.
There is a difference in how individuals respond. One way or another, I'd want a doctor who's committed to monitoring your T/E ratio. Having a good ratio is very important. It's better if you can get there naturally, bc it eliminates sides. If you get high estrogen, if he's monitoring you, you can gradually introduce and adjust an estrogen blocker until you hit a desired level.
There are different types. Some can just crush estrogen, which more research is suggesting has a lot of sides. Some are less drastic and will just reduce the level, not eliminate.
There is a difference in how individuals respond. One way or another, I'd want a doctor who's committed to monitoring your T/E ratio. Having a good ratio is very important. It's better if you can get there naturally, bc it eliminates sides. If you get high estrogen, if he's monitoring you, you can gradually introduce and adjust an estrogen blocker until you hit a desired level.
Posted on 2/28/20 at 4:45 pm to lattin1
quote:
Huh? No. Some people's estrogen levels might be fine on a TRT dose but other's will have elevated E2 levels that are above what's considered ideal.
I was probably too broad with my original post. Checking levels for a good balance of T/E is the ideal.
I tend to think most reasonably healthy people will get there naturally based on some of the meta studies, but that's no reason not to have consistent checkups to make sure. I probably should have emphasized monitoring with my original post.
I just tend to think too often an Estrogen blocker is a default, when it comes with its own side effects.
Posted on 2/28/20 at 5:14 pm to Rep520
Testosterone aromatizes at different rates for different people. There's really no rhyme or reason behind it. Even at 200mg of Test C a week my estrogen levels were above the nominal range so the doctor gave me Arimidex. If you don't need it, you don't need it. That being said, whenever I go on a blast and run higher Test and or other compounds I'll typically let my estrogen levels run a little higher because like you said, it serves a purpose.
Posted on 2/28/20 at 5:20 pm to lattin1
Yeah, that's why I'm not sure we disagree, just I wasn't super clear initially. I was trying to advocate the start with nothing and add a blocker if, and only to the extent, necessary.
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